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ptNew opened postdoctoral position at INSERM
Obesity and diabetes are currently increasing, in spite of the numerous public health campaigns and interventions. Alongside the nutritional and lifestyle improvement advices, the interest of novel therapeutic approaches have to limit the global epidemics of diabetes and obesity. The therapeutic approaches (pharrmacologic or surgical) currently available can be improved by the discovery of novel agents. The post-doctoral position consists in investigating the insulin-like effect of novel SSAO substrates, more powerful than benzylamine.
Next Events & workshops attended by DIOmed partners
"Fira de Recerca en Directe" organized by Obra Social de Caixa Catalunya and the Parc Científic de Barcelona , has been held in Barcelona (SPAIN) from 20th to 22nd April 2010.
The Fair was an exhibition about current research of which main objective was to contribute to encourage scientific culture among general public and let know about all current projects developed in Barcelona. Both researchers and public could interact during experimentations with lab instruments and IRB Barcelona had their own experimentation stand called: Could an existing drug be used to improve obesity and diabetes?
More info at:
http://obrasocial.caixacatalunya.cat/osocial/idiomes/2/fitxers/cultura/recerca/index.htm
"4th Congress of the International Society of Nutrigenetics/Nutrigenomics - From reference intakes to personalized nutrition" organized by University of Pamplona and the ISSN , will be held in Pamplona (SPAIN) from 18th to 20th November 2010.
Christian Carpéné, INSERM (FR) will attend as Commitee Member.
More info at: http://www.isnn2010navarra.com
New results for type 2 diabetes, Antonio Zorzano
There may be hope for young adults suffering from type 2 diabetes, according to new research. Writing in the journal Diabetes Care, the researchers from Ireland, Spain and Italy investigated how new mechanisms in muscle cells may elucidate severe insulin resistance in the body, and showed a reduced response to aerobic exercise in young obese patients with type 2 diabetes. The study's results are part of the DIABESITY ('Novel molecular drug targets for obesity and type 2 diabetes') project, funded under the 'Life sciences, genomics and biotechnology for health' Thematic area of the EU's Sixth Framework Programme (FP6) to the tune of EUR 11.6 million. [+ information]
PhD co-tutelle thesis obtained on february 15th 2010 at Semmelweis University, Budapest and at Paul Sabatier University, Toulouse.
Obesity and diabetes are serious problems in the developed countries and considerable efforts are put in the development of drugs improving impaired carbohydrate metabolism. Semicarbazide sensitive amine oxidase (SSAO) may be a possible target. The enzyme catalyzes the oxidation of primary amines. SSAO is highly expressed in adipocytes and in the vasculature. [+ information]
New CTP net, Christian Carpéné
The network, entitled "Potential role of mediterranean diet components in the treatments of obesity, hyperlipidaemia and diabetes" has been designed to share expertise of research teams in Nutrition and Metabolism working on both sides of the Pyrenees on metabolic diseases: Obesity and diabetes and their complications... [+ information]
Past events
DIOMED Consortium Meeting, 20 November, 2009, Barcelona
In the first progress meeting, have been discussed scientific and technical aspects related to the progres of the project.
Discussions have mainly been focused on progress made on GT 2 - "Continous surveillance of needs and opportunities, GT 3 - "Development of technology tools to support the discovery, development and licensing of drugs for the treatment of diabetes and obesity" and GT 4 - "Identification of active compounds for the treatment of obesity and diabetes with the licensing potential". All the partners gave their inputs.
Next progress meeting will be scheduled within 6 months.
DIOMED KICK-OFF MEETING, 22nd May 2009
Events and Conferences
|
Date and Place |
Type and Title |
Attendees |
Other description |
|
|---|---|---|---|---|
|
14-15 November 2008
|
Oral Presentation |
"Molecular Switches Regulating Adipocyte Biology" |
J.E.Pessin (USA), A.Zorzano (Spain)
|
Inside Cost Action: Adipose Tissue Project |
|
8 April 2009,IBIS- CSIC Sevilla (Spain) |
Seminar |
"Dinámica mitocondrial, metabolismo y enfermedad" |
Antonio Zorzano |
IBIS - CSIC Plenary Seminars Instituto de Biomedicina de Sevilla |
|
1-4 Avril 2009, Nice |
Oral Presentation |
Orally given benzylamine improves glucose tolerance in mice rendered diabetic by high-fat diet. |
Iffiú-Soltész Z., Wanecq E., Szökő É., Portillo M., Milagro F. & Carpéné C |
3rd International congress on prediabetes and the metabolic syndrome, Publié dans : J. Diabet. 2009, 1, suppl.1, A241. |
|
13-16 Mai 2009, Fulda |
Oral Presentation |
Histamine oxidation is mainly controlled by AOC3 amine oxidase in mouse adipose tissue |
Iffiú-Soltész Z., Wanecq E., Prévot D., Grès S. & Carpéné C. |
38th EHRS meeting, Publié dans : Inflamm. Res. 2009, in press. |
|
2 Juin 2009, Toulouse |
Oral Presentation |
L’administration orale de benzylamine améliore la tolérance au glucose chez des souris soumises à une diète hyperlipidique. |
Iffiú-Soltész Z., Wanecq E., Prévot D., Szökő É., Rodriguez V., Portillo M. P., Lomba A., Milagro F. I. & Carpéné C. |
25 ème journée de Chimie-Biologie, |
|
11-13 Juin 2009 |
Oral Presentation |
Influencia de la tiramina en administración crónica sobre el desarollo del tejido adiposo y la tolerancia a la glucosa en rodeores normoglicemicos |
Iffiú-Soltész Z., Turpin D., Schaak S., Wanecq E., Prévot D., Atgié C. & Carpéné C. |
XI Congreso Nacional de la Sociedad Española de Nutrición, Sitges, Publié dans : Nutricion Hospitalaria, 2010, 25, 152. |
|
6-11 September 2009,Lucca (Italy) |
Conference attendeance |
"Insulin Resistance" |
Dr. Antonio Zorzano, IRB (ES) as Chair |
"GLUCOSE TRANSPORTER BIOLOGY AND DIABETES"Il Ciocco Resort Lucca, Tuscany, Italy inside Summer Research Conferences Faseb https://secure.faseb.org/faseb/meetings/Summrconf/Programs/11806.pdf |
|
26 October 2009,Bordeaux |
Workshop attended |
"Discussion Workshop on Eukaryotic expression" |
Dr. Pedro Castanheira, BIOCANT (PT) |
Institute of Microbiology, Academy of Sciences of Czech Republic |
|
14 November 2009,Ljubljana (Slovenia)
|
Oral Presentation- Workshop |
"Bridging mitochondrial dynamics and metabolism in muscle" |
Antonio Zorzano |
>"Muscle and Fat: Molecular mechanisms of signalling and crosstalk", Celica Biomedical Center & University of Ljubljana (Slovenia) inside "Adipose Tissue: A Key Target for Prevention of the Metabolic Syndrome Symposium" |
|
10-12 Décembre 2009, Montpellier |
Oral Presentation |
Influence of tyramine supplementation on adiposity, glucose tolerance and heart rate variability in mice. |
Carpéné C., Iffiú-Soltész Z., Turpin D., Atgié C., Wanecq E., Prévot D. & Schaak S. |
4ème Congrès de la Société Française de Nutrition |
|
04-05 December 2009,Düsseldorf (Germany)
|
Oral Presentation - Workshop |
"Expression of genes encoding mitochondrial proteins in extreme forms of type 2 diabetes" |
Antonio Zorzano
|
The Metabolic Syndrome: A Challenge for Molecular Medicine, Maritim Hotel, Düsseldorf (Germany) |
|
1-2 Mars 2010, Reus |
Oral Presentation |
Efecto del antidepresivo fenelzina sobre la adiposidad en ratas y sobre la respuesta lipolítica y lipogénica en adipocitos humanos y de roedores. |
Mercader J., Lomba A., Brenachot X., Milagro F. I. & Carpéné C. |
Simposium nacional de Obesidad : aspectos bàsicos y aplicados, Publié dans : Nutricion Hospitalaria, 2010, in press. |
|
1-2 Mars 2010, Reus |
Oral Presentation |
Influencia de la administracion de tiramina sobre la adiposidad en rodeores normoglucemicos |
Carpéné C., Schaak S., Atgié C., Iffiu-Soltesz Z. & Valet P. |
Simposium nacional de Obesidad : aspectos bàsicos y aplicados,Publié dans : Nutricion Hospitalaria, 2010, in press. |
|
23-25 Mars 2010,Bordeaux |
Oral Presentation |
Influence of the antidepressant phenelzine on in vivo lipid deposition in rodents and on in vitro lipogenesis in adipocytes |
Iffiú-Soltész Z., Lomba A., Valet P., Martinez A. J., Milagro F. I. & Carpéné C. |
Congrès de Physiologie, Pharmacologie et Thérapeutique, Publié dans : Fundament. Clin. Pharmacol., 2010, in press. |
|
23-25 Mars 2010,Bordeaux |
Oral Presentation |
Influence of the antidepressant phenelzine on in vivo lipid deposition in rodents and on in vitro lipogenesis in adipocytes |
Iffiú-Soltész Z., Lomba A., Valet P., Martinez A. J., Milagro F. I. & Carpéné C. |
Congrès de Physiologie, Pharmacologie et Thérapeutique, Publié dans : Fundament. Clin. Pharmacol., 2010, in press. |
|
18-20 November 2010,Pamplona (Spain) |
Congress attendance |
"4th Congress of the International Society of Nutrigenetics/Nutrigenomics - From reference intakes to personalized nutrition" |
Christian Carpéné |
Christian Carpéné as Committee Member |
|
20-22 April 2010, Barcelona(Spain) |
Exhibition |
"¿Puede un fármaco ya existente servir para mejorar la obesidad y la diabetes?" |
IRB Barcelona |
"Fira de Recerca en Directe",La Obra Social de Caixa Catalunya y el Parc Científic de Barcelona . |
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